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Columbus

Beauty Care Products

High Quality Raw Material Cyclosporin A

Columbus, Ohio - 01 Mar, 2018
  • $12

Description

High Quality Raw Material Cyclosporin A

Product Name: Cyclosporin A
CAS: 59865-13-3
MF: C62H111N11O12
MW: 1202.61
Chemical Properties:White Crystalline Powder
Assay: 99.5%

Description:
Cyclosporin A is a hydrophobic cyclic peptide isolated from several fungal species including Cylindrocarpon, Fusarium, Trichoderma and Tolypocladium. Cyclosporin A inhibits T-cell activation and has been marketed since 1983 as an immunosuppressant in post-allogeneic organ transplant. Cyclosporin A acts by binding to the protein, cyclophilin (immunophilin), in T-lymphocytes causing inhibition of calcineurin (protein phosphatase 2B). Cyclosporin A reduces transcription of interleukin 2, and inhibits lymphokine production, interleukin release and NO synthesis induced by interleukin 1α, lipopolysaccharides and TNFα.

Usage :
Cyclosporine is used to prevent organ rejection in people who have received a liver, kidney, or heart transplant. It is usually taken along with other medications to allow your new organ to function normally. Cyclosporine belongs to a class of drugs known as immunosuppressants.


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