Oxycodone 80 mg is a prescription opioid medication used for severe pain in carefully selected patients under the supervision of a qualified healthcare professional. Because high-dose oxycodone carries significant risks, it should be used exactly as prescribed and never shared with another person. Patients concerned about medication costs can speak with their doctor or pharmacist about legitimate options, including generic alternatives, insurance coverage, pharmacy savings programs, or other clinically appropriate pain-management treatments. Prescription costs may differ depending on the pharmacy, location, insurance, and applicable regulations.